Description

4-Isopropoxy-1H-Pyrrolo[2,3-B]Pyridine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily sought after by research institutions and pharmaceutical companies developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, functional group transformations, and the construction of complex polycyclic systems.
• Agrochemical Research: Serves as an intermediate in the development of novel crop protection agents and pesticides.
• Material Science: Potential use in the synthesis of organic electronic materials and specialty polymers.

Basic Information

Product Name	4-Isopropoxy-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	937797-32-5
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine, 4-(1-methylethoxy)-; 4-Isopropoxy-1H-pyrrolo[2,3-b]pyridine; 4-(Propan-2-yloxy)-1H-pyrrolo[2,3-b]pyridine; 4-Isopropoxy-7-azaindole; 4-(Isopropyloxy)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridin-4-ol, isopropyl ether; 4-Isopropoxy-1H-7-azaindole
EINECS	Contact for details

Quality Control

Our 4-Isopropoxy-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.