Description

(6S)-2-Benzyl-6-(tert-Butyldimethylsilyloxy)Cyclohexanone CAS NO 937740-23-3 is a high-purity chiral synthon featuring a benzyl group and a protected hydroxyl moiety. This compound is a critical intermediate in the synthesis of complex pharmaceutical molecules, particularly those requiring stereochemical control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of chiral drugs, including potential antiviral and anti-inflammatory agents.
• Asymmetric Synthesis: Used as a precursor in stereoselective reactions to construct complex molecular architectures with defined chirality.
• Medicinal Chemistry Research: Employed in R&D for structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic Research: A valuable reagent for methodological studies in organic synthesis and catalysis at universities and research institutes.

Basic Information

Product Name	(6S)-2-Benzyl-6-(tert-Butyldimethylsilyloxy)Cyclohexanone
CAS No.	937740-23-3
Molecular Formula	C19H30O2Si
Molecular Weight	318.53 g/mol
Synonyms	(6S)-2-Benzyl-6-[(tert-Butyldimethylsilyl)oxy]cyclohexanone; (6S)-6-[(tert-Butyldimethylsilyl)oxy]-2-benzylcyclohexanone; (6S)-2-Benzyl-6-(TBDMSO)cyclohexanone; (S)-2-Benzyl-6-(tert-butyldimethylsilyloxy)cyclohexanone; 2-Benzyl-6-[(tert-butyldimethylsilyl)oxy]cyclohexanone, (6S)-; Cyclohexanone, 2-benzyl-6-[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (6S)-; TBDMS-protected (S)-2-benzyl-6-hydroxycyclohexanone
EINECS	Contact for details

Quality Control

Our (6S)-2-Benzyl-6-(tert-Butyldimethylsilyloxy)Cyclohexanone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.