Description

Methyl 3-Bromo-5-Fluorophenylacetate, 96% is a high-purity fluorinated and brominated aromatic ester building block. This compound is valued for its dual halogen functionality, which provides distinct reactivity for selective cross-coupling and substitution reactions in advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the bromo-fluoro substitution pattern confers specific biological activity.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and liquid crystals with tailored electronic properties.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for Suzuki, Stille, and Negishi coupling reactions to form biaryl structures.
• Functional Group Transformation: The ester group can be hydrolyzed to the corresponding acid or reduced to the alcohol, enabling further derivatization.
• Chemical Biology Probes: Used in the synthesis of labeled compounds or molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	Methyl 3-Bromo-5-Fluorophenylacetate, 96%
CAS No.	937732-38-2
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	Methyl (3-bromo-5-fluorophenyl)acetate; 3-Bromo-5-fluorophenylacetic acid methyl ester; Methyl 2-(3-bromo-5-fluorophenyl)acetate; (3-Bromo-5-fluorophenyl)acetic acid methyl ester; Methyl α-(3-bromo-5-fluorophenyl)acetate; 937732-38-2; Methyl 3-bromo-5-fluoro-benzeneacetate
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-5-Fluorophenylacetate, 96% is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR). A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.