Description

2-[3-Cyclopropyl-4-(Difluoromethyl)-6-(4-Methoxyphenyl)Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly in creating targeted therapies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers specializing in heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel pyrazolopyridine-based drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• API Development: Serves as a precursor in the development of potential active pharmaceutical ingredients targeting various disease pathways.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	2-[3-Cyclopropyl-4-(Difluoromethyl)-6-(4-Methoxyphenyl)Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	937607-32-4
Molecular Formula	C21H19F2N3O3
Molecular Weight	399.39 g/mol
Synonyms	2-[3-Cyclopropyl-4-(difluoromethyl)-6-(4-methoxyphenyl)pyrazolo[3,4-b]pyridin-1-yl]acetic acid; 2-(3-Cyclopropyl-4-(difluoromethyl)-6-(4-methoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; 937607-32-4; Acetic acid, 2-[3-cyclopropyl-4-(difluoromethyl)-6-(4-methoxyphenyl)pyrazolo[3,4-b]pyridin-1-yl]-; Pyrazolo[3,4-b]pyridine-1-acetic acid derivative
EINECS	Contact for details

Quality Control

Our 2-[3-Cyclopropyl-4-(Difluoromethyl)-6-(4-Methoxyphenyl)Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.