Description

2-[3-Cyclopropyl-4-(Difluoromethyl)-6-Phenyl-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active ingredients. This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the development of targeted therapies. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for drug discovery and development programs.

Application

• Key intermediate in the synthesis of novel kinase inhibitors and other targeted small-molecule therapeutics.
• Building block for pharmaceutical research and development (R&D) in oncology and inflammatory disease pathways.
• Precursor for the development of PET (Positron Emission Tomography) tracer molecules for diagnostic imaging.
• Used in process chemistry for scale-up and optimization of API (Active Pharmaceutical Ingredient) manufacturing routes.
• Valuable scaffold in combinatorial chemistry and high-throughput screening libraries for lead identification.
• Reference standard for analytical method development and quality control in pharmaceutical production.

Basic Information

Product Name	2-[3-Cyclopropyl-4-(Difluoromethyl)-6-Phenyl-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	937607-25-5
Molecular Formula	C19H15F2N3O2
Molecular Weight	355.34 g/mol
Synonyms	2-(3-Cyclopropyl-4-(difluoromethyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; 1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 3-cyclopropyl-4-(difluoromethyl)-6-phenyl-; 937607-25-5; 2-[3-Cyclopropyl-4-(difluoromethyl)-6-phenylpyrazolo[3,4-b]pyridin-1-yl]ethanoic acid; 3-Cyclopropyl-4-(difluoromethyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-1-acetic Acid
EINECS	Contact for details

Quality Control

Our 2-[3-Cyclopropyl-4-(Difluoromethyl)-6-Phenyl-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.