Description

2-[3-Cyclopropyl-4-(Difluoromethyl)-6-(2-Furyl)Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapies, particularly within oncology and anti-inflammatory drug discovery pipelines. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies in early-stage drug discovery.
• Contract Research Organization (CRO) & CDMO Support: Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Oncology Drug Development: Employed in the research and development of targeted cancer therapies due to its specific pyrazolopyridine core.
• Biochemical Reagent: May be utilized as a reference standard or a tool compound in biochemical assays and pharmacological profiling.
• Academic Research: Used in university and institutional labs for advanced organic synthesis projects and heterocyclic chemistry studies.

Basic Information

Item	Details
Product Name	2-[3-Cyclopropyl-4-(Difluoromethyl)-6-(2-Furyl)Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	937607-24-4
Molecular Formula	C₁₈H₁₅F₂N₃O₃
Molecular Weight	359.33 g/mol
Synonyms	2-(3-Cyclopropyl-4-(difluoromethyl)-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; 2-[3-Cyclopropyl-4-(difluoromethyl)-6-(2-furyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid; 1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 3-cyclopropyl-4-(difluoromethyl)-6-(2-furanyl)-; 937607-24-4; 2-(3-cyclopropyl-4-(difluoromethyl)-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)ethanoic acid
EINECS	Contact for details

Quality Control

Every batch of 2-[3-Cyclopropyl-4-(Difluoromethyl)-6-(2-Furyl)Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity suitable for research and development applications. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and analytical methods are provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled with appropriate precautions for chemicals soluble in strong acid/organic solvent. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.