Description

2-[6-Cyclopropyl-4-(Difluoromethyl)-3-Methyl-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily needed by research institutions, custom synthesis laboratories, and pharmaceutical companies engaged in the development of new drug candidates, especially within oncology and antiviral research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug molecules and investigational new chemical entities.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop compounds with improved efficacy and pharmacokinetic profiles.
• Custom Synthesis & Contract Manufacturing: A key starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client R&D programs.
• API Development: Integral to the development pathway of new Active Pharmaceutical Ingredients, particularly for targeted therapies.
• Biochemical Reagent: May be utilized as a specialized reagent or reference standard in biochemical assays and mechanistic studies.

Basic Information

Product Name	2-[6-Cyclopropyl-4-(Difluoromethyl)-3-Methyl-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	937607-09-5
Molecular Formula	C14H13F2N3O2
Molecular Weight	293.27 g/mol
Synonyms	2-(6-Cyclopropyl-4-(difluoromethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; 1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 6-cyclopropyl-4-(difluoromethyl)-3-methyl-; 937607-09-5; 2-[6-Cyclopropyl-4-(difluoromethyl)-3-methylpyrazolo[3,4-b]pyridin-1-yl]ethanoic acid; 6-Cyclopropyl-4-(difluoromethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-1-acetic Acid
EINECS	Contact for details

Quality Control

Our 2-[6-Cyclopropyl-4-(Difluoromethyl)-3-Methyl-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be handled in accordance with good laboratory practices for strong acids/organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.