Description

1-(3-Nitropyridin-2-Yl)Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique nitropyridine-piperidine carboxylic acid hybrid structure. This compound is essential for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a critical building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to develop new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Research: Serves as a synthetic intermediate for developing new crop protection agents and pesticides.
• Chemical Synthesis Reagent: Employed in organic synthesis for constructing complex heterocyclic frameworks and functional molecules.
• Biochemical Research: Potential use in developing enzyme inhibitors or molecular probes for biological studies.
• Material Science Applications: Investigated as a monomer or precursor for specialty polymers and advanced functional materials.

Basic Information

Product Name	1-(3-Nitropyridin-2-Yl)Piperidine-3-Carboxylic Acid
CAS No.	937606-75-2
Molecular Formula	C11H13N3O4
Molecular Weight	251.24 g/mol
Synonyms	3-Carboxy-1-(3-nitro-2-pyridinyl)piperidine; Piperidine-3-carboxylic acid, 1-(3-nitro-2-pyridinyl)-; 1-(3-Nitro-2-pyridyl)piperidine-3-carboxylic acid; 1-(3-Nitropyridin-2-yl)piperidine-3-carboxylic acid; 937606-75-2; 1-(3-Nitropyridin-2-yl)piperidine-3-carboxylic acid; 1-(3-Nitro-2-pyridinyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(3-Nitropyridin-2-Yl)Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines and customer-specific requirements. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.