Description

[6-(2-Methoxyphenyl)-3-Methyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is a high-value, multifunctional heterocyclic building block featuring a pyrazolopyridine core. This compound is engineered for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. Its complex structure, incorporating a trifluoromethyl group and a methoxyphenyl moiety, makes it a critical intermediate for medicinal chemists and process development scientists seeking to modulate the biological activity, metabolic stability, and physicochemical properties of new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in therapeutic areas such as oncology, inflammation, and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a specialized monomer or additive in the development of advanced organic electronic materials or functional polymers.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	[6-(2-Methoxyphenyl)-3-Methyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	937605-90-8
Molecular Formula	C19H16F3N3O3
Molecular Weight	391.35 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 6-(2-methoxyphenyl)-3-methyl-4-(trifluoromethyl)-; (6-(2-Methoxyphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; Pyrazolopyridine acetic acid derivative; 937605-90-8; AGN-PC-0JSTP5; AKOS025310626; ZINC000006714947; SCHEMBL23346811
EINECS	Contact for details

Quality Control

Every batch of [6-(2-Methoxyphenyl)-3-Methyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and LC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.