Description

[6-(2-Furyl)-3-Methyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is a high-value, multifunctional heterocyclic building block featuring a fused pyrazolopyridine core. This compound matters for its unique structural motifs, including the furan and trifluoromethyl groups, which are critical for modulating the physicochemical and biological properties of advanced molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, as well as by material scientists exploring specialty polymers and electronic materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Active Ingredient Precursor: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazolopyridine scaffold.
• Material Science Research: Investigated as a building block for organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its conjugated system and functional handles.
• Chemical Biology & Probe Development: Employed in the design of fluorescent probes or enzyme inhibitors for biochemical and diagnostic applications.
• Academic & Contract Research: Utilized in universities and CROs for methodological studies in heterocyclic and fluorine chemistry.
• Custom Synthesis & Scale-Up: Supplied for process development and pilot-scale production under cGMP or ISO quality systems for clinical trial material.

Basic Information

Product Name	[6-(2-Furyl)-3-Methyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	937605-78-2
Molecular Formula	C15H10F3N3O3
Molecular Weight	337.26 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 6-(2-furanyl)-3-methyl-4-(trifluoromethyl)-; (6-(Furan-2-yl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; Furan-substituted Trifluoromethyl Pyrazolopyridine Acetic Acid; FTMPP Acetic Acid; CAS 937605-78-2
EINECS	Contact for details

Quality Control

Our [6-(2-Furyl)-3-Methyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure compliance with stringent specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support development projects with custom purity grades and can align with cGMP, ICH Q7, and other relevant regulatory guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is compatible with strong acids and organic solvents but should be kept away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.