Description

(3-Cyclopropyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly kinase inhibitors. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting protein kinases for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• Biochemical Tool Compound: Serves as a precursor for labeled probes or inhibitors used in biochemical and cellular assays to study biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	(3-Cyclopropyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Acetic Acid
CAS No.	937605-64-6
Molecular Formula	C11H11N3O2
Molecular Weight	217.23 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 3-cyclopropyl-; (3-Cyclopropyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; 2-(3-Cyclopropyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; 937605-64-6; (3-Cyclopropyl-pyrazolo[3,4-b]pyridin-1-yl)-acetic acid; Acetic acid, (3-cyclopropyl-1H-pyrazolo[3,4-b]pyridin-1-yl)-
EINECS	Contact for details

Quality Control

Our (3-Cyclopropyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.