Description

[1,3-Dimethyl-6-Oxo-4-(Trifluoromethyl)-1,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Acetic Acid is a high-value, heterocyclic organic compound featuring a pyrazolopyridine core with a trifluoromethyl group and an acetic acid side chain. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) for the research and development of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for small molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Protease Inhibitor Development: The structural motif suggests potential application in creating inhibitors for various enzymatic targets.
• Kinase Inhibitor Synthesis: Serves as a core scaffold for the development of kinase-targeted therapeutics in oncology and inflammatory diseases.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	[1,3-Dimethyl-6-Oxo-4-(Trifluoromethyl)-1,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Acetic Acid
CAS No.	937605-40-8
Molecular Formula	C₁₁H₁₀F₃N₃O₃
Molecular Weight	289.21 g/mol
Synonyms	1,3-Dimethyl-6-oxo-4-(trifluoromethyl)-1,6-dihydro-7H-pyrazolo[3,4-b]pyridin-7-ylacetic acid; 7H-Pyrazolo[3,4-b]pyridin-7-ylacetic acid, 1,3-dimethyl-6-oxo-4-(trifluoromethyl)-1,6-dihydro-; 937605-40-8; 1,3-Dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-7(6H)-one-7-acetic acid; (1,3-Dimethyl-6-oxo-4-(trifluoromethyl)-1,6-dihydro-7H-pyrazolo[3,4-b]pyridin-7-yl)acetic acid
EINECS	Contact for details

Quality Control

Our production of [1,3-Dimethyl-6-Oxo-4-(Trifluoromethyl)-1,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Acetic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.