Description

2-[4-(2,2-Difluoroethoxy)Phenyl]Acetic Acid is a high-purity fluorinated aromatic acetic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity and properties imparted by the difluoroethoxy moiety, enabling precise molecular construction for high-value end products. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to build complex molecules with enhanced biological activity or specific physical characteristics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atoms can improve compound stability and membrane permeability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components in electronic display and lighting technologies.
• Organic Synthesis & Medicinal Chemistry Research: Employed in academic and industrial R&D labs for constructing complex molecular libraries and exploring structure-activity relationships (SAR).
• Fluorinated Polymer Modification: Acts as a monomer or modifier to introduce specific functional groups into specialty polymers, enhancing material properties.

Basic Information

Product Name	2-[4-(2,2-Difluoroethoxy)Phenyl]Acetic Acid
CAS No.	937602-66-9
Molecular Formula	C10H10F2O3
Molecular Weight	216.18 g/mol
Synonyms	4-(2,2-Difluoroethoxy)phenylacetic Acid; [4-(2,2-Difluoroethoxy)phenyl]acetic Acid; 2-(4-(2,2-Difluoroethoxy)phenyl)acetic Acid; α-(4-(2,2-Difluoroethoxy)phenyl)acetic Acid; DFEPA; Difluoroethoxy Phenylacetic Acid; (4-(2,2-Difluoroethoxy)phenyl)ethanoic Acid
EINECS	Contact for details

Quality Control

Our production of 2-[4-(2,2-Difluoroethoxy)Phenyl]Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. Our facilities operate under a quality system designed to meet the expectations of cGMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.