Description

1,3-Bis(4-Fluorophenyl)-2-Methylpropane-1,3-Dione is a specialized fluorinated diketone building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring two fluorinated aromatic rings, makes it a valuable precursor for creating complex heterocyclic compounds and functional materials. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, potentially targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in the synthesis of novel fluorinated pesticides and herbicides, where the fluorine atoms can enhance biological activity, metabolic stability, and lipophilicity.
• Material Science Precursor: Serves as a building block for fluorinated polymers, ligands for metal-organic frameworks (MOFs), and advanced organic electronic materials.
• Chemical Synthesis: Employed in organic reactions such as Claisen condensations, cyclizations, and as a chelating agent for metal catalysis due to its β-diketone functionality.
• Academic & Industrial R&D: Essential for methodological studies in fluoroorganic chemistry and the discovery of new chemical entities in contract research organizations (CROs).

Basic Information

Product Name	1,3-Bis(4-Fluorophenyl)-2-Methylpropane-1,3-Dione
CAS No.	937602-30-7
Molecular Formula	C₁₇H₁₄F₂O₂
Molecular Weight	288.29 g/mol
Synonyms	2-Methyl-1,3-bis(4-fluorophenyl)propane-1,3-dione; 1,3-Di(4-fluorophenyl)-2-methyl-1,3-propanedione; 2-Methyl-1,3-bis(p-fluorophenyl)-1,3-propanedione; 4,4'-Difluorodibenzoylmethane, 2-Methyl derivative; 2-Methyl-1,3-di(4-fluorophenyl)propane-1,3-dione; 1,3-Propanedione, 1,3-bis(4-fluorophenyl)-2-methyl-
EINECS	Contact for details

Quality Control

Our 1,3-Bis(4-Fluorophenyl)-2-Methylpropane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.