Description

n-Methyl-5-(Trifluoromethyl)-2-Pyridinamine is a high-value, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its core value lies in the unique combination of the pyridinamine scaffold and the electron-withdrawing trifluoromethyl group, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, where its structural features can enhance metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Material Science Precursor: Employed in the synthesis of specialized ligands for catalysis and functional monomers for advanced polymers.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes and tool compounds used in biochemical and cellular assay development.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	n-Methyl-5-(Trifluoromethyl)-2-Pyridinamine
CAS No.	937602-15-8
Molecular Formula	C7H7F3N2
Molecular Weight	176.14 g/mol
Synonyms	2-Amino-5-(trifluoromethyl)-N-methylpyridine; 5-(Trifluoromethyl)-2-(methylamino)pyridine; N-Methyl-5-(trifluoromethyl)pyridin-2-amine; 2-(Methylamino)-5-(trifluoromethyl)pyridine; 5-Trifluoromethyl-2-methylaminopyridine; 937602-15-8; N-Methyl-5-trifluoromethyl-2-pyridinamine
EINECS	Contact for details

Quality Control

Our n-Methyl-5-(Trifluoromethyl)-2-Pyridinamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles for pharmaceutical-grade intermediates, and our quality commitment extends to meeting the stringent requirements of research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its chemical nature as a fluoride/strong alkali-sensitive compound, it should be kept separate from incompatible materials. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.