Description

6-(Thiophen-3-Yl)Nicotinonitrile is a high-value heterocyclic building block featuring a fused thiophene and pyridine core. This compound matters as a critical intermediate in modern pharmaceutical and agrochemical research, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Building block for novel herbicides, fungicides, and insecticides requiring specific heterocyclic motifs.
• Material Science: Precursor for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Chemical Synthesis: Versatile starting material for further functionalization via the nitrile group (e.g., hydrolysis to acids, reduction to amines).
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-(Thiophen-3-Yl)Nicotinonitrile
CAS No.	937601-80-4
Molecular Formula	C10H6N2S
Molecular Weight	186.23 g/mol
Synonyms	3-(3-Thienyl)-5-cyanopyridine; 5-Cyano-3-(3-thienyl)pyridine; 6-(3-Thienyl)nicotinonitrile; 3-(Thiophen-3-yl)-5-pyridinecarbonitrile; 6-(Thiophen-3-yl)pyridine-3-carbonitrile; Nicotinonitrile, 6-(3-thienyl)-; 6-(Thiophen-3-yl)nicotinonitrile
EINECS	Contact for details

Quality Control

Our 6-(Thiophen-3-Yl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.