Description

1-(2-Cyanophenyl)-4-Piperidinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct piperidine-carboxylic acid scaffold. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop new drug candidates and ensure scalable, reproducible synthesis processes.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in neurological and psychiatric research.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) targeting specific receptors.
• Medicinal Chemistry R&D: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Fine Chemical Production: Employed in the manufacture of high-value, specialty chemicals for the life sciences industry.
• Reference Standard: Can be utilized as a certified reference material (CRM) for analytical method development and quality control.
• Biochemical Research: Applied in the study of enzyme inhibitors and other biologically active molecules.

Basic Information

Product Name	1-(2-Cyanophenyl)-4-Piperidinecarboxylic Acid
CAS No.	937601-79-1
Molecular Formula	C13H14N2O2
Molecular Weight	230.26 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-(2-cyanophenyl)-; 1-(2-Cyanophenyl)piperidine-4-carboxylic acid; 2-(4-Carboxypiperidin-1-yl)benzonitrile; 1-(2-Cyanophenyl)-4-carboxypiperidine; 1-(2-Cyanophenyl)isonipecotic acid; Benzonitrile, 2-(4-carboxy-1-piperidinyl)-; 937601-79-1; 1-(2-Cyano-phenyl)-piperidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Cyanophenyl)-4-Piperidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.