Description

6-Cyclopropyl-1-(4-Methoxyphenyl)-3-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
• Drug Discovery & Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) within the pyrazolopyridine chemical class.
• Process Chemistry & Scale-Up: Serves as a standardized building block for process optimization and pilot-scale manufacturing of target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	6-Cyclopropyl-1-(4-Methoxyphenyl)-3-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	937600-18-5
Molecular Formula	C19H17N3O3
Molecular Weight	335.36 g/mol
Synonyms	6-Cyclopropyl-1-(4-methoxyphenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1-(4-Methoxyphenyl)-3-methyl-6-cyclopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6-cyclopropyl-1-(4-methoxyphenyl)-3-methyl-; CAS 937600-18-5
EINECS	Contact for details

Quality Control

Our production of 6-Cyclopropyl-1-(4-Methoxyphenyl)-3-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous specifications, with comprehensive Certificates of Analysis (COA) provided. Our quality systems support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.