Description

1-Benzyl-6-Cyclopropyl-3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid CAS NO 937598-78-2 is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of investigational new drugs, especially within kinase inhibitor research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures due to its fused heterocyclic core.
• Research & Development (R&D): Essential for academic and industrial labs conducting structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a critical intermediate in the scaled-up production of target APIs under GMP conditions.
• Biochemical Research: Potential use as a tool compound or probe for studying biological mechanisms in vitro.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-Benzyl-6-Cyclopropyl-3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	937598-78-2
Molecular Formula	C19H17N3O2
Molecular Weight	319.36 g/mol
Synonyms	1-Benzyl-6-cyclopropyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 1-benzyl-6-cyclopropyl-1,7-dihydro-3-methyl-pyrazolo[3,4-b]pyridine-; 937598-78-2; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-benzyl-6-cyclopropyl-3-methyl-; Benzyl-cyclopropyl-methyl-pyrazolopyridine-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Benzyl-6-Cyclopropyl-3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in the original packaging away from direct light and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.