Description

6-Cyclopropyl-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel small-molecule drug candidates. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers engaged in developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged pyrazolopyridine scaffold.
• Agrochemical Development: Serves as a precursor in the research of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthesis projects.
• Library Synthesis: A valuable input for creating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	6-Cyclopropyl-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	937597-44-9
Molecular Formula	C12H11N3O2
Molecular Weight	229.24 g/mol
Synonyms	6-Cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1-Methyl-6-cyclopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 4-Pyrazolo[3,4-b]pyridinecarboxylic acid, 6-cyclopropyl-1-methyl-; 937597-44-9; 6-Cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6-cyclopropyl-1-methyl-
EINECS	Contact for details

Quality Control

Our 6-Cyclopropyl-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.