Description

4-Pyridinemethanol, 2-Chloro-.Alpha.-Methyl-, (.Alpha.R)- is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. This compound matters for its role in the stereoselective synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material science industries seeking to incorporate its specific stereochemistry into their target compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands used in asymmetric catalysis to control reaction stereochemistry.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry, particularly in exploring new asymmetric synthetic routes.

Basic Information

Product Name	4-Pyridinemethanol, 2-Chloro-.Alpha.-Methyl-, (.Alpha.R)-
CAS No.	937399-97-8
Molecular Formula	C7H8ClNO
Molecular Weight	157.60 g/mol
Synonyms	(αR)-2-Chloro-α-methyl-4-pyridinemethanol; (R)-2-Chloro-α-methyl-4-pyridinemethanol; (R)-2-Chloro-α-methylpyridin-4-ylmethanol; 2-Chloro-α-methyl-4-pyridinemethanol (αR)-; 4-Pyridinemethanol, 2-chloro-α-methyl-, (αR)-; (R)-2-Chloro-α-methyl-4-picolyl alcohol; (R)-1-(2-Chloropyridin-4-yl)ethanol
EINECS	Contact for details

Quality Control

Our 4-Pyridinemethanol, 2-Chloro-.Alpha.-Methyl-, (.Alpha.R)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.