Description

1-(5-Chloropyridin-2-Yl)Ethanamine is a high-value chloropyridine derivative serving as a critical building block in advanced organic synthesis. Its primary commercial value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and chemical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, insecticides, and fungicides, leveraging the bioactivity of the chloropyridine moiety.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other transition metal complexes.
• Material Science Research: Intermediate for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.
• Academic and R&D Laboratories: Used in medicinal chemistry programs and methodological research for novel synthetic route exploration.

Basic Information

Product Name	1-(5-Chloropyridin-2-Yl)Ethanamine
CAS No.	937399-51-4
Molecular Formula	C7H9ClN2
Molecular Weight	156.61 g/mol
Synonyms	1-(5-Chloropyridin-2-yl)ethan-1-amine; 1-(5-Chloro-2-pyridinyl)ethanamine; 1-(5-Chloro-2-pyridyl)ethylamine; 5-Chloro-2-(1-aminoethyl)pyridine; N1-(5-Chloropyridin-2-yl)ethanamine; α-Aminoethyl-5-chloropyridine; 2-(1-Aminoethyl)-5-chloropyridine
EINECS	Contact for details

Quality Control

Our 1-(5-Chloropyridin-2-Yl)Ethanamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.