Description

3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Indazole is a high-value, synthetically versatile boronic ester derivative of indazole, serving as a critical building block in modern organic synthesis. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: A vital reagent for methodology development and complex molecule synthesis in research laboratories worldwide.
• Ligand Synthesis: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Indazole
CAS No.	937366-55-7
Molecular Formula	C₁₃H₁₇BN₂O₂
Molecular Weight	244.10 g/mol
Synonyms	1H-Indazole, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 3-Indazoleboronic acid pinacol ester; 3-(Pinacolatoboryl)-1H-indazole; 1H-Indazol-3-ylboronic acid pinacol ester; 3-Boron-1H-indazole pinacol ester; 937366-55-7
EINECS	Contact for details

Quality Control

Our production of 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Indazole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and LC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.