Description

Pinacol Ester Indole-5-Boronic Acid is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of indole-based drug candidates, including kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with complex heterocyclic structures.
• Material Science: Serves as a precursor for organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation reagents.
• Catalyst & Ligand Development: Used to synthesize novel ligands for transition metal catalysis.
• Academic & Contract Research: A versatile reagent for method development and discovery chemistry in R&D laboratories.

Basic Information

Product Name	Pinacol Ester Indole-5-Boronic Acid
CAS No.	937366-54-6
Molecular Formula	C₁₄H₁₈BNO₂
Molecular Weight	243.11 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; Indole-5-boronic acid pinacol ester; 1H-Indole-5-boronic acid, pinacol ester; 5-(Pinacolatoboryl)-1H-indole; 5-Indoleboronic acid pinacol ester; 5-Boronoindole pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indole
EINECS	Contact for details

Quality Control

Our Pinacol Ester Indole-5-Boronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and maintain stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.