Description

tert-Butyl 4-Hydroxypyridin-2-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is critical for the synthesis of complex molecules, offering a protected carbamate group and a reactive hydroxypyridine scaffold for further functionalization. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development and production of novel pesticides, herbicides, and plant growth regulators.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic compounds and functionalized pyridine derivatives.
• Chemical Biology & Medicinal Chemistry: Employed in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential monomer or additive in the research of specialty polymers and functional materials.

Basic Information

Product Name	tert-Butyl 4-Hydroxypyridin-2-Ylcarbamate
CAS No.	937263-39-3
Molecular Formula	C10H14N2O3
Molecular Weight	210.23 g/mol
Synonyms	2-(((tert-Butoxy)carbonyl)amino)-4-hydroxypyridine; 4-Hydroxy-2-pyridinylcarbamic Acid 1,1-Dimethylethyl Ester; tert-Butyl N-(4-hydroxypyridin-2-yl)carbamate; 2-(tert-Butoxycarbonylamino)-4-hydroxypyridine; Boc-4-hydroxypyridin-2-ylamine; 4-Hydroxy-2-((tert-butoxycarbonyl)amino)pyridine; 2-Amino-4-hydroxypyridine tert-butylcarbamate; tert-Butyl (4-hydroxypyridin-2-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Hydroxypyridin-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.