Description

1-Pyrrolidinecarboxylic Acid, 2-(2-Bromoethyl)-, 1,1-Dimethylethyl Ester, (2S)- is a high-purity, chiral building block of significant importance in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. Pharmaceutical research organizations and fine chemical manufacturers need this material for its utility in introducing functionalized pyrrolidine scaffolds, which are prevalent in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Peptidomimetic Research: Used to incorporate constrained, functionalized proline analogs into peptide backbones to enhance metabolic stability and biological activity.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Ligand and Catalyst Development: Employed in the preparation of novel chiral ligands and organocatalysts for use in stereoselective transformations.
• Agrochemical Synthesis: Utilized in the research and development of advanced, chiral active ingredients for crop protection.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	1-Pyrrolidinecarboxylic Acid, 2-(2-Bromoethyl)-, 1,1-Dimethylethyl Ester, (2S)-
CAS No.	937203-20-8
Molecular Formula	C11H20BrNO2
Molecular Weight	278.19 g/mol
Synonyms	(2S)-2-(2-Bromoethyl)-1-(tert-butoxycarbonyl)pyrrolidine; (S)-2-(2-Bromoethyl)-1-Boc-pyrrolidine; tert-Butyl (2S)-2-(2-bromoethyl)-1-pyrrolidinecarboxylate; (S)-1-Boc-2-(2-bromoethyl)pyrrolidine; 1-Boc-2-(2-bromoethyl)-(S)-pyrrolidine; (S)-N-Boc-2-(2-bromoethyl)pyrrolidine; 1-(tert-Butoxycarbonyl)-2-(2-bromoethyl)-(S)-pyrrolidine; (2S)-1-(tert-Butoxycarbonyl)-2-(2-bromoethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylic Acid, 2-(2-Bromoethyl)-, 1,1-Dimethylethyl Ester, (2S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.