Description

4-[2-(4-Amino-1,2,5-Oxadiazol-3-Yl)-1-Ethyl-7-[(3S)-3-Piperidinylmethoxy]-1H-Imidazo[4,5-C]Pyridin-4-Yl]-2-Methyl-3-Butyn-2-Ol is a high-purity, complex heterocyclic compound designed for advanced research and development applications. This molecule is of significant interest in medicinal chemistry due to its intricate structure, which combines imidazopyridine, oxadiazole, and piperidine motifs, offering a versatile scaffold for pharmacological exploration. It is primarily targeted toward pharmaceutical R&D organizations, biotechnology companies, and academic institutions engaged in the discovery and synthesis of novel therapeutic agents, particularly in areas such as kinase inhibition or targeted oncology.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potential drug candidates, especially for targeted cancer therapies.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Biochemical Probe Development: Acts as a precursor for developing selective probes to study specific enzyme pathways or protein-protein interactions in biological systems.
• Kinase Inhibitor Research: The structural features suggest potential application in the design and synthesis of novel kinase inhibitors for oncology and inflammatory diseases.
• Preclinical Development: Supplied in milligram to gram quantities for use in early-stage in vitro and in vivo efficacy and safety studies.
• Custom Synthesis Starting Material: Provides a sophisticated starting point for contract research organizations (CROs) and custom synthesis houses to develop proprietary analogs for clients.

Basic Information

Product Name	4-[2-(4-Amino-1,2,5-Oxadiazol-3-Yl)-1-Ethyl-7-[(3S)-3-Piperidinylmethoxy]-1H-Imidazo[4,5-C]Pyridin-4-Yl]-2-Methyl-3-Butyn-2-Ol
CAS No.	937174-76-0
Molecular Formula	C22H27N7O3
Molecular Weight	437.50 g/mol
Synonyms	4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol; (3S)-1-Ethyl-7-(3-piperidinylmethoxy)-4-[2-methyl-1,1-dimethyl-2-propynyl]-1H-imidazo[4,5-c]pyridine-2-carboxamide 3-oxide; CAS 937174-76-0; 1H-Imidazo[4,5-c]pyridine-2-carboxamide, 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol derivative.
EINECS	Contact for details

Quality Control

Every batch of 4-[2-(4-Amino-1,2,5-Oxadiazol-3-Yl)-1-Ethyl-7-[(3S)-3-Piperidinylmethoxy]-1H-Imidazo[4,5-C]Pyridin-4-Yl]-2-Methyl-3-Butyn-2-Ol is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity, purity, and impurity profile testing using advanced analytical techniques such as HPLC, NMR, and MS to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.