Description

Ethyl 2-((S)-3-Amino-2-Oxopiperidin-1-Yl)Acetate Hcl is a high-purity chiral piperidinone derivative, a critical building block in modern pharmaceutical synthesis. This compound is valued for its role as a key intermediate in the development of novel therapeutic agents, particularly protease inhibitors and other small-molecule drugs. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in advanced active pharmaceutical ingredient (API) development.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the multi-step synthesis of complex drug candidates, especially those targeting enzymatic pathways.
• Protease Inhibitor Research: Serves as a core structural component in the research and development of novel protease inhibitors for treating viral infections and other diseases.
• Medicinal Chemistry: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes to improve drug potency and selectivity.
• Pre-clinical & Clinical API Manufacturing: Employed in the scaled-up production of Active Pharmaceutical Ingredients (APIs) for pre-clinical trials and early-phase clinical studies.
• Custom Synthesis: A starting material for the custom synthesis of more complex, proprietary molecules for specialized therapeutic applications.

Basic Information

Product Name	Ethyl 2-((S)-3-Amino-2-Oxopiperidin-1-Yl)Acetate Hydrochloride
CAS No.	937057-79-9
Molecular Formula	C9H17ClN2O3
Molecular Weight	236.70 g/mol
Synonyms	1-Acetic acid, 2-[(3S)-3-amino-2-oxo-1-piperidinyl]-, ethyl ester, hydrochloride; Ethyl (S)-2-(3-amino-2-oxopiperidin-1-yl)acetate hydrochloride; (S)-Ethyl 2-(3-amino-2-oxopiperidin-1-yl)acetate HCl; 1-Piperidineacetic acid, 3-amino-2-oxo-, ethyl ester, hydrochloride, (3S)-; Ethyl 2-((3S)-3-amino-2-oxo-1-piperidinyl)acetate hydrochloride; 937057-79-9; (S)-3-Amino-2-oxopiperidin-1-yl-acetic acid ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 2-((S)-3-Amino-2-Oxopiperidin-1-Yl)Acetate Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.