Description

trans-1-(2,5-Dioxopyrrolidin-1-Yl) 4-Methyl Cyclohexane-1,4-Dicarboxylate is a high-purity, functionalized cyclohexane derivative designed for advanced chemical synthesis. This compound serves as a critical building block and coupling agent in the development of complex molecules, offering precise reactivity and structural control. It is essential for research and production in the pharmaceutical, agrochemical, and specialty polymer industries, where its unique ester-activated succinimide moiety enables efficient conjugation and material modification.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for conjugating drug molecules to carriers or modifying bioavailability.
• Bioconjugation Reagent: Used for labeling proteins, peptides, and antibodies due to its reactivity with primary amines, facilitating the creation of diagnostic and therapeutic bioconjugates.
• Polymer Modification: Employed to introduce functional cross-linking sites or reactive handles into polymer backbones for advanced material science applications.
• Agrochemical Synthesis: Serves as a versatile intermediate in creating novel herbicides, fungicides, and plant growth regulators with tailored properties.
• Peptide Synthesis: Acts as an activated ester coupling agent in solid-phase and solution-phase peptide synthesis for efficient amide bond formation.
• Surface Functionalization: Used to modify the surface properties of nanoparticles, sensors, and other materials to impart specific chemical functionality.

Basic Information

Item	Details
Product Name	trans-1-(2,5-Dioxopyrrolidin-1-Yl) 4-Methyl Cyclohexane-1,4-Dicarboxylate
CAS No.	936901-99-4
Molecular Formula	C15H19NO6
Molecular Weight	309.32 g/mol
Synonyms	4-Methyl-1,4-cyclohexanedicarboxylic acid 1-(2,5-dioxo-1-pyrrolidinyl) ester; 1,4-Cyclohexanedicarboxylic acid, 4-methyl-, 1-(2,5-dioxo-1-pyrrolidinyl) ester, trans-; trans-4-Methyl-1,4-cyclohexanedicarboxylic acid N-hydroxysuccinimide ester; trans-4-Methylcyclohexane-1,4-dicarboxylic acid 1-(2,5-dioxopyrrolidin-1-yl) ester; 936901-99-4; NSC 936901-99-4; trans-1-(N-Succinimidyl) 4-methyl cyclohexane-1,4-dicarboxylate
EINECS	Contact for details

Quality Control

Our trans-1-(2,5-Dioxopyrrolidin-1-Yl) 4-Methyl Cyclohexane-1,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our production adheres to cGMP principles where applicable, supporting its use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.