Description

3-Methoxy-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its methoxy and trifluoromethyl substituents. This compound matters for its unique electronic properties and stability, making it a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs). It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine-containing motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or fluorinated liquid crystals.
• Chemical Biology Probes: Utilized to build fluorinated analogs of natural products or biochemical probes for mechanism-of-action studies.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring precise functionalization on the pyridine ring.

Basic Information

Product Name	3-Methoxy-4-(Trifluoromethyl)Pyridine
CAS No.	936841-72-4
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	4-(Trifluoromethyl)-3-methoxypyridine; 3-Methoxy-4-(trifluoromethyl)pyridine; 3-Methoxy-4-trifluoromethylpyridine; 3-Methoxypyridine, 4-(trifluoromethyl)-; Pyridine, 3-methoxy-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Methoxy-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.