Description

3-Hydroxy-4-(Trifluoromethyl)Pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a hydroxyl group with a trifluoromethyl substituent on the pyridine ring, makes it an essential intermediate for creating molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Chemical Biology & Proteomics: Useful as a building block for designing molecular probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	3-Hydroxy-4-(Trifluoromethyl)Pyridine
CAS No.	936841-71-3
Molecular Formula	C6H4F3NO
Molecular Weight	163.10 g/mol
Synonyms	4-(Trifluoromethyl)pyridin-3-ol; 3-Pyridinol, 4-(trifluoromethyl)-; 4-Trifluoromethyl-3-hydroxypyridine; 3-Hydroxy-4-trifluoromethylpyridine; 4-(Trifluoromethyl)-3-pyridinol
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.