Description

2-tert-Butyl 4-Methyl 3,4-Dihydroisoquinoline-2,4(1H)-Dicarboxylate (Wx142477) is a high-purity, synthetic organic compound belonging to the dihydroisoquinoline class, serving as a critical building block in advanced chemical synthesis. Its value lies in providing a versatile and protected scaffold for the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. This intermediate is essential for R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key protected precursor in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators with specific biological activity.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing dihydroisoquinoline and tetrahydroisoquinoline cores prevalent in natural products and bioactive molecules.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, catalysts, and organic frameworks used in advanced material applications.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in the pharmaceutical industry.

Basic Information

Product Name	2-tert-Butyl 4-Methyl 3,4-Dihydroisoquinoline-2,4(1H)-Dicarboxylate (Wx142477)
CAS No.	936828-99-8
Molecular Formula	C₁₇H₂₁NO₄
Molecular Weight	303.35 g/mol
Synonyms	1,2,3,4-Tetrahydro-2-[(1,1-dimethylethoxy)carbonyl]-4-[(methoxycarbonyl)methyl]isoquinoline; 2-(tert-Butoxycarbonyl)-4-(methoxycarbonylmethyl)-1,2,3,4-tetrahydroisoquinoline; 2-tert-Butoxycarbonyl-4-methoxycarbonylmethyl-1,2,3,4-tetrahydroisoquinoline; Wx-142477; Wx142477; tert-Butyl 4-(methoxycarbonylmethyl)-3,4-dihydro-1H-isoquinoline-2-carboxylate; 2-tert-Butyl 4-methyl 1,2,3,4-tetrahydroisoquinoline-2,4-dicarboxylate
EINECS	Contact for details

Quality Control

Every batch of 2-tert-Butyl 4-Methyl 3,4-Dihydroisoquinoline-2,4(1H)-Dicarboxylate (Wx142477) is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.