Description

4-Oxospiro[Chroman-2,4'-Piperidine]-6-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic molecular architecture. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel, small-molecule therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in hit-to-lead optimization.
• Protease Inhibitor Development: The structural motif is relevant for research into inhibitors of specific enzymatic targets.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	4-Oxospiro[Chroman-2,4'-Piperidine]-6-Carbonitrile
CAS No.	936802-28-7
Molecular Formula	C15H14N2O2
Molecular Weight	254.29 g/mol
Synonyms	6-Cyano-4-oxospiro[chroman-2,4'-piperidine]; 4-Oxospiro[2H-1-benzopyran-2,4'-piperidine]-6-carbonitrile; Spiro[chroman-2,4'-piperidine]-4-one, 6-cyano-; 936802-28-7; 4-Oxo-spiro(chromane-2,4'-piperidine)-6-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Oxospiro[Chroman-2,4'-Piperidine]-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.