Description

2-Bromo-4-(((tert-Butyldimethylsilyl)Oxy)Methyl)Thiazole is a high-value, organosilicon-protected thiazole derivative, primarily utilized as a sophisticated synthetic intermediate. Its core value lies in the tert-butyldimethylsilyl (TBDMS) protecting group, which offers exceptional stability for sensitive functional groups during complex multi-step syntheses. This compound is essential for researchers and manufacturers in pharmaceutical development and advanced organic chemistry, particularly for constructing novel heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those containing thiazole or modified thiazole cores.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and insecticides where the thiazole moiety imparts biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialized polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & R&D Synthesis: A valuable reagent for methodological development in organic synthesis, particularly in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	2-Bromo-4-(((tert-Butyldimethylsilyl)Oxy)Methyl)Thiazole
CAS No.	936691-31-5
Molecular Formula	C10H18BrNOSSi
Molecular Weight	308.30 g/mol
Synonyms	2-Bromo-4-(((tert-butyldimethylsilyl)oxy)methyl)thiazole; 4-(((tert-Butyldimethylsilyl)oxy)methyl)-2-bromothiazole; 2-Bromo-4-((tert-butyldimethylsiloxy)methyl)thiazole; TBDMS-protected 2-Bromo-4-(hydroxymethyl)thiazole; 2-Bromo-4-((TBDMS-O)methyl)thiazole; 936691-31-5; Thiazole, 2-bromo-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(((tert-Butyldimethylsilyl)Oxy)Methyl)Thiazole is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.