Description

1-(Pyrimidin-2-Yl-Methyl)-2-(Pyrimidin-2-Yl)-Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a unique bis-pyrimidinyl structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its defined structure enables precise molecular design for targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Building Block: Used in combinatorial chemistry and high-throughput screening libraries to explore novel chemical space and structure-activity relationships (SAR).
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, or plant growth regulators with potential new modes of action.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and protein-protein interactions within biological systems.
• Ligand Synthesis for Catalysis: Acts as a precursor for creating novel chiral ligands used in asymmetric synthesis and homogeneous catalysis.
• Academic & Institutional Research: Employed in university and government labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	1-(Pyrimidin-2-Yl-Methyl)-2-(Pyrimidin-2-Yl)-Propanoic Acid
CAS No.	936643-76-4
Molecular Formula	C13H12N4O2
Molecular Weight	256.26 g/mol
Synonyms	2-(Pyrimidin-2-yl)-1-(pyrimidin-2-ylmethyl)propanoic acid; 1-(Pyrimidin-2-ylmethyl)-2-(pyrimidin-2-yl)propanoic acid; α-(Pyrimidin-2-yl)-β-(pyrimidin-2-ylmethyl)propionic acid; Bis(pyrimidin-2-yl)propanoic acid derivative; 2-Pyrimidin-2-yl-1-(pyrimidin-2-ylmethyl)propionic acid; (2-Pyrimidin-2-yl-1-pyrimidin-2-ylmethyl-ethyl)-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(Pyrimidin-2-Yl-Methyl)-2-(Pyrimidin-2-Yl)-Propanoic Acid is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.