Description

A-Tosyl-(2-Bromobenzyl) Isocyanide is a specialized organic building block featuring both an isocyanide functional group and a tosyl-protected amine moiety. This compound matters for its versatility as a key precursor in multi-component reactions, enabling the efficient synthesis of complex heterocyclic scaffolds and pharmacophores. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of novel drug candidates, particularly for constructing nitrogen-containing heterocycles via Ugi and Passerini reactions.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides by creating diverse chemical libraries.
• Chemical Biology Probe Development: Serves as a versatile handle for synthesizing activity-based probes to study enzyme function and protein interactions.
• Material Science: Employed in the creation of functional polymers and smart materials with tailored properties.
• Academic & Contract Research: Essential for methodological development in organic synthesis and for producing custom compounds in research laboratories.

Basic Information

Product Name	A-Tosyl-(2-Bromobenzyl) Isocyanide
CAS No.	936548-16-2
Molecular Formula	C15H12BrNO2S
Molecular Weight	350.23 g/mol
Synonyms	N-[(2-Bromophenyl)methyl]-4-methylbenzenesulfonamide isocyanide; 2-Bromo-N-(isocyanomethyl)benzenesulfonamide, N-tosyl derivative; Tosyl-(2-bromobenzyl) isocyanide; p-Toluenesulfonyl-(2-bromobenzyl) isocyanide; (2-Bromobenzyl)(tosyl)methyl isocyanide; 936548-16-2; ATBIC (abbreviation)
EINECS	Contact for details

Quality Control

Our A-Tosyl-(2-Bromobenzyl) Isocyanide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.