Description

4-(5-Amino-6-Methyl-2-Pyridinyl)-1-Piperazinecarboxylic Acid 1,1-Dimethylethyl Ester is a high-value, multi-functional piperazine-pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a protected carboxylic acid and a primary amine, makes it an essential intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization due to its versatile piperazine and aminopyridine moieties.
• Process Chemistry & Scale-Up: Serves as a validated starting material or intermediate in the pilot-scale and commercial-scale synthesis of target drug molecules.
• Custom Synthesis & Contract Manufacturing: A requested compound for custom synthesis projects, enabling the production of bespoke chemical libraries and specialized derivatives.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.

Basic Information

Product Name	4-(5-Amino-6-Methyl-2-Pyridinyl)-1-Piperazinecarboxylic Acid 1,1-Dimethylethyl Ester
CAS No.	936368-54-6
Molecular Formula	C15H24N4O2
Molecular Weight	292.38 g/mol
Synonyms	tert-Butyl 4-(5-amino-6-methylpyridin-2-yl)piperazine-1-carboxylate; 1-Boc-4-(5-amino-6-methyl-2-pyridyl)piperazine; 4-(5-Amino-6-methyl-2-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(5-amino-6-methyl-2-pyridinyl)piperazine; 936368-54-6; Boc-4-(5-amino-6-methyl-2-pyridyl)piperazine; tert-Butyl 4-(5-amino-6-methyl-2-pyridinyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

We supply 4-(5-Amino-6-Methyl-2-Pyridinyl)-1-Piperazinecarboxylic Acid 1,1-Dimethylethyl Ester with a standard purity of ≥95% (HPLC), with higher grades (≥98%, ≥99%) available to meet specific project requirements. Our products undergo rigorous quality testing to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥95.0%
Purity (HPLC, Area %)	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.