Description

5-Bromo-2-(4-Fluoro-Benzyloxy)-Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a halogenated pyridine core with a fluorinated benzyloxy substituent. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals, where its specific bromine and fluorine atoms enable precise molecular modifications. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drugs, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its halogenated structure for enhanced biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its aromatic and halogenated framework.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	5-Bromo-2-(4-Fluoro-Benzyloxy)-Pyridine
CAS No.	936343-08-7
Molecular Formula	C12H9BrFNO
Molecular Weight	282.11 g/mol
Synonyms	5-Bromo-2-[(4-fluorophenyl)methoxy]pyridine; 2-(4-Fluorobenzyloxy)-5-bromopyridine; 5-Bromo-2-(4-fluorobenzyloxy)pyridine; Pyridine, 5-bromo-2-[(4-fluorophenyl)methoxy]-; 936343-08-7; 5-Br-2-(4-F-BnO)-Pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-(4-Fluoro-Benzyloxy)-Pyridine is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.