Description

Spiro[Indene-1,4'-Piperidine]-3-Carboxylic Acid CAS NO 936138-15-7 is a high-value, multifunctional spirocyclic building block in advanced organic synthesis. Its unique fused-ring structure, combining indene and piperidine motifs with a carboxylic acid handle, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a privileged scaffold in medicinal chemistry for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, receptor modulators, and other therapeutic areas.
• Agrochemical Research: Used as a key building block in the development of new pesticides and herbicides, leveraging its spirocyclic core for enhanced biological activity and stability.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes and tool compounds for studying biological pathways and protein-ligand interactions.
• Material Science Precursor: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Catalyst and Ligand Development: Utilized in the design and synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	Spiro[Indene-1,4'-Piperidine]-3-Carboxylic Acid
CAS No.	936138-15-7
Molecular Formula	C15H17NO2
Molecular Weight	243.30 g/mol
Synonyms	1'H-Spiro[indene-1,4'-piperidine]-3-carboxylic acid; 3-Carboxyspiro[indene-1,4'-piperidine]; Spiro(indane-1,4'-piperidine)-3-carboxylic acid; 936138-15-7; Spirocyclic indene-piperidine carboxylic acid; 1,2-Dihydrospiro[indene-1,4'-piperidine]-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our Spiro[Indene-1,4'-Piperidine]-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications from early-stage R&D to pre-clinical development under ISO guided standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.