Description

4-Chloro-2-Iodobenzeneacetic Acid Methyl Ester is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. This compound matters as a versatile intermediate, enabling the precise construction of complex molecular architectures through its reactive ester and halogen functional groups. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as drug discovery, process chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Research: Used in the development and scale-up of new herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the presence of the iodine atom.
• Ligand and Material Science: Employed as a building block for synthesizing specialized ligands for catalysis or advanced organic materials.
• Chemical Derivatization: The methyl ester group allows for further functionalization, including hydrolysis to the corresponding acid or transesterification.

Basic Information

Product Name	4-Chloro-2-Iodobenzeneacetic Acid Methyl Ester
CAS No.	936098-39-4
Molecular Formula	C9H8ClIO2
Molecular Weight	310.52 g/mol
Synonyms	Methyl (4-Chloro-2-iodophenyl)acetate; 2-(4-Chloro-2-iodophenyl)acetic Acid Methyl Ester; Methyl 2-(4-Chloro-2-iodophenyl)acetate; 4-Chloro-2-iodobenzeneacetic Acid Methyl Ester; (4-Chloro-2-iodophenyl)acetic Acid Methyl Ester; Methyl 4-Chloro-2-iodobenzeneacetate; 936098-39-4; 4-Chloro-2-iodo-α-toluic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Iodobenzeneacetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and identity, typically meeting standards suitable for research and process development. Certificates of Analysis (COA) detailing purity (by HPLC/GC), identity (by IR, NMR), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Typical 98-99%)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.