Description

6-Trifluoromethyl-Imidazo[1,2-A]Pyridine is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique imidazopyridine core, functionalized with a trifluoromethyl group, imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, as well as by specialty chemical manufacturers producing advanced materials and ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral programs.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products, leveraging the bioactivity of the imidazopyridine scaffold.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands in OLEDs or charge-transport materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag due to its distinct fluorine signature for NMR studies.
• Catalyst & Ligand Development: Utilized in the design of novel metal-organic frameworks (MOFs) and asymmetric catalysis ligands.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	6-Trifluoromethyl-Imidazo[1,2-A]Pyridine
CAS No.	936009-02-8
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	6-(Trifluoromethyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 6-(trifluoromethyl)-; 6-Trifluoromethylimidazo[1,2-a]pyridine; 6-(Trifluoromethyl)-1H-imidazo[1,2-a]pyridine; 6-Trifluoromethyl-1H-imidazo[1,2-a]pyridine; TFMP-Imidazopyridine; 6-CF3-Imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl-Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder/crystals
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.