Description

2-Bromo-5-Fluoro-4-Nitropyridine 1-Oxide is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular modification is required. Its unique halogenated and oxidized pyridine structure makes it an essential intermediate for medicinal chemistry, particularly in the synthesis of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with novel modes of action.
• Material Science: Serves as a precursor for creating functionalized ligands and complexing agents used in catalysis and advanced materials.
• Chemical Synthesis: A versatile reagent for introducing bromo, fluoro, and nitro substituents onto the pyridine N-oxide scaffold in multi-step synthetic routes.
• Academic & R&D: Essential for exploratory research in heterocyclic and medicinal chemistry within university and corporate laboratories.

Basic Information

Product Name	2-Bromo-5-Fluoro-4-Nitropyridine 1-Oxide
CAS No.	935534-40-0
Molecular Formula	C5H2BrFN2O3
Molecular Weight	236.98 g/mol
Synonyms	2-Bromo-5-fluoro-4-nitropyridine N-oxide; 4-Nitro-2-bromo-5-fluoropyridine 1-oxide; 2-Bromo-5-fluoro-4-nitropyridine 1-oxide; Pyridine, 2-bromo-5-fluoro-4-nitro-, 1-oxide; 935534-40-0; 2-Bromo-5-fluoro-4-nitropyridine N-oxide; 4-Nitro-2-bromo-5-fluoropyridine N-oxide
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Fluoro-4-Nitropyridine 1-Oxide is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical research and production processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.