Description

3,4-Dihydrospiro[Chromene-2,4'-Piperidin]-4-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic molecular architecture. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs, particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new therapeutic agents.
• Drug Discovery Scaffold: Used as a core structural motif in medicinal chemistry for creating libraries of novel compounds with potential biological activity.
• Chemical Biology Research: Employed as a probe or tool compound to study biological pathways and protein interactions.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot and commercial production.
• Academic Research: Utilized in universities and research institutes for synthetic organic chemistry studies and methodology development.

Basic Information

Product Name	3,4-Dihydrospiro[Chromene-2,4'-Piperidin]-4-Ol
CAS No.	935534-37-5
Molecular Formula	C13H17NO2
Molecular Weight	219.28 g/mol
Synonyms	4-Hydroxy-3,4-dihydrospiro[chromene-2,4'-piperidine]; 4-Hydroxy-1'-azaspiro[chromene-2,4'-piperidine]; 4-Hydroxy-3,4-dihydro-1'H-spiro[chromene-2,4'-piperidine]; Spiro[chromene-2,4'-piperidin]-4-ol, 3,4-dihydro-; 935534-37-5; 3,4-Dihydrospiro[2H-1-benzopyran-2,4'-piperidin]-4-ol
EINECS	Contact for details

Quality Control

Our 3,4-Dihydrospiro[Chromene-2,4'-Piperidin]-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with client specifications and current industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.