Description

tert-Butyl 4-[(3-Iodopyridin-2-Yl)Sulfonyl]Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing molecules with specific biological activity. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• API Development: Serves as a critical synthon in the pilot-scale and commercial-scale production of active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and methodological development.

Basic Information

Product Name	tert-Butyl 4-[(3-Iodopyridin-2-Yl)Sulfonyl]Piperazine-1-Carboxylate
CAS No.	935534-36-4
Molecular Formula	C14H18IN3O4S
Molecular Weight	451.28 g/mol
Synonyms	1-Boc-4-[(3-iodopyridin-2-yl)sulfonyl]piperazine; tert-Butyl 4-(3-iodopyridine-2-sulfonyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-[(3-iodo-2-pyridinyl)sulfonyl]piperazine; 935534-36-4; BOC-Piperazine Sulfonyl Iodopyridine Derivative; 4-[(3-Iodo-2-pyridinyl)sulfonyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[(3-Iodopyridin-2-Yl)Sulfonyl]Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.