Description

4(Aminomethyl)1H,3Hpyrrolo[2,3B]Pyridin2One is a high-purity, heterocyclic organic compound featuring a fused pyrrolopyridinone core with an aminomethyl functional group. This unique structure makes it a valuable and versatile pharmaceutical intermediate and building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its privileged scaffold.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of new therapeutic agents.
• Bioconjugation and Probe Synthesis: The reactive aminomethyl group allows for conjugation to fluorophores, biotin, or other molecules to create chemical probes for biological studies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	4(Aminomethyl)1H,3Hpyrrolo[2,3B]Pyridin2One
CAS No.	935466-94-7
Molecular Formula	C8H9N3O
Molecular Weight	163.18 g/mol
Synonyms	4-(Aminomethyl)-1H,3H-pyrrolo[2,3-b]pyridin-2-one; 4-(Aminomethyl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one; 4-(Aminomethyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-2-one; 4-(Aminomethyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one; 935466-94-7; 4-Aminomethyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
EINECS	Contact for details

Quality Control

Our 4(Aminomethyl)1H,3Hpyrrolo[2,3B]Pyridin2One is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support development and commercial projects with material suitable for research use, development, and can discuss cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.