Description

4-(6-Chloropyridin-3-Yl)Tetrahydro-2H-Pyran-4-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining pyridine and tetrahydropyran motifs. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation insecticides and herbicides, leveraging its chloropyridine moiety.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Ligand and Catalyst Preparation: Utilized in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science: Potential building block for functionalized polymers and advanced organic materials.

Basic Information

Product Name	4-(6-Chloropyridin-3-Yl)Tetrahydro-2H-Pyran-4-Carbonitrile
CAS No.	935279-87-1
Molecular Formula	C11H11ClN2O
Molecular Weight	222.67 g/mol
Synonyms	4-(6-Chloro-3-pyridinyl)tetrahydro-2H-pyran-4-carbonitrile; 4-(6-Chloropyridin-3-yl)oxane-4-carbonitrile; 4-(6-Chloro-3-pyridyl)tetrahydropyran-4-carbonitrile; 4-(6-Chloro-3-pyridinyl)-4-cyanotetrahydropyran; 4-(6-Chloropyridin-3-yl)tetrahydro-2H-pyran-4-carbonitrile; Tetrahydro-2H-pyran-4-carbonitrile, 4-(6-chloro-3-pyridinyl)-; 935279-87-1
EINECS	Contact for details

Quality Control

Our 4-(6-Chloropyridin-3-Yl)Tetrahydro-2H-Pyran-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.