Description

4-(Isocyanatomethyl)Tetrahydropyran is a specialized isocyanate derivative featuring a tetrahydropyran ring, offering unique reactivity and structural properties. This compound is a valuable building block in advanced organic synthesis, particularly for creating polymers and functional materials with tailored performance characteristics. It is primarily utilized by research and development chemists, as well as industrial manufacturers in the pharmaceutical, agrochemical, and specialty polymer sectors seeking to incorporate its distinct heterocyclic isocyanate functionality.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel active pharmaceutical ingredients (APIs), especially those requiring a rigid, oxygen-containing heterocycle.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the tetrahydropyran moiety can influence bioavailability and activity.
• Polymer & Resin Modification: Acts as a reactive monomer or cross-linking agent in the synthesis of polyurethanes, polyureas, and other specialty polymers to enhance properties like chemical resistance, adhesion, or flexibility.
• Material Science Research: Employed in the development of advanced materials, including coatings, adhesives, and elastomers with specific thermal or mechanical profiles.
• Chemical Linker: Functions as a versatile spacer or linker in bioconjugation chemistry and for the synthesis of complex molecular architectures.

Basic Information

Product Name	4-(Isocyanatomethyl)Tetrahydropyran
CAS No.	934570-48-6
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	4-(Isocyanatomethyl)oxane; Tetrahydropyran-4-ylmethyl isocyanate; 4-(Isocyanatomethyl)tetrahydro-2H-pyran; Oxan-4-ylmethyl isocyanate; THP-methyl isocyanate
EINECS	Contact for details

Quality Control

Our 4-(Isocyanatomethyl)Tetrahydropyran is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay by HPLC, identification by FT-IR and NMR, and impurity profiling to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and reactive isocyanate nature, store under a dry, inert atmosphere (e.g., nitrogen or argon) in a cool, well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from moisture, heat, and incompatible materials such as strong bases, alcohols, amines, and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.