Description

2-(2-Methoxyphenyl)-4,4,6-Trimethyl-1,3,2-Dioxaborinane is a specialized organoboron reagent, specifically a cyclic boronic ester, with the CAS number 934558-37-9. This compound is valued for its enhanced stability and reactivity profile compared to simple boronic acids, making it a crucial intermediate in modern synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common motif in active pharmaceutical ingredients (APIs) and organic electronic materials.
• Pharmaceutical Intermediate: Used in the research and production of drug candidates, particularly those containing substituted biphenyl or heterobiaryl structures.
• Agrochemical Synthesis: Serves as a precursor in creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Employed in the development of organic light-emitting diodes (OLEDs), liquid crystals, and polymers where precise boron incorporation is required.
• Chemical Biology & Proteomics: Can be utilized as a handle for bioconjugation or in the synthesis of molecular probes and inhibitors.
• Catalyst and Ligand Development: Acts as a precursor for novel boron-containing catalysts or ligands in asymmetric synthesis.

Basic Information

Product Name	2-(2-Methoxyphenyl)-4,4,6-Trimethyl-1,3,2-Dioxaborinane
CAS No.	934558-37-9
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	2-(2-Methoxyphenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane; 2-Methoxyphenyl-4,4,6-trimethyl-1,3,2-dioxaborinane; o-Methoxyphenyl MIDA Boronate; (2-Methoxyphenyl)boronic acid MIDA ester; 2-(2-Methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (common boronic ester analogue); B-[2-(Methoxyphenyl)]-4,4,6-trimethyl-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Our 2-(2-Methoxyphenyl)-4,4,6-Trimethyl-1,3,2-Dioxaborinane is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity (typically by NMR and HPLC), identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening containers to prevent hydrolysis and maintain reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.