Description

(+/-)-4-Amino-3,4-Dihydro-6-Fluoro-Spiro[2H-1-Benzopyran-2,1'-Cyclobutane is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and benzopyran structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel therapeutic agents targeting central nervous system and cardiovascular disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel spirocyclic compounds with potential biological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• API Development: Serves as a precursor in the development of Active Pharmaceutical Ingredients (APIs) targeting neurological pathways.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme and receptor functions.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening campaigns.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	(+/-)-4-Amino-3,4-Dihydro-6-Fluoro-Spiro[2H-1-Benzopyran-2,1'-Cyclobutane
CAS No.	934554-58-2
Molecular Formula	C13H16FNO
Molecular Weight	221.27 g/mol
Synonyms	4-Amino-6-fluoro-3,4-dihydrospiro[2H-1-benzopyran-2,1'-cyclobutane]; 6-Fluoro-4-amino-3,4-dihydrospiro[chromene-2,1'-cyclobutane]; 934554-58-2; 4-Amino-6-fluoro-3,4-dihydro-2H-spiro[chromene-2,1'-cyclobutane]; (±)-4-Amino-6-fluoro-3,4-dihydrospiro[chromene-2,1'-cyclobutane]; 6-Fluoro-4-aminospiro[chroman-2,1'-cyclobutane]; Spiro[cyclobutane-1,2'-chroman]-4-amine, 6'-fluoro-3',4'-dihydro-
EINECS	Contact for details

Quality Control

Our (+/-)-4-Amino-3,4-Dihydro-6-Fluoro-Spiro[2H-1-Benzopyran-2,1'-Cyclobutane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.