Description

4-(1-Amino-Ethyl)-Benzoic Acid Methyl Ester Hydrochloride is a high-purity organic salt, primarily utilized as a key chiral intermediate in advanced pharmaceutical synthesis. Its value lies in providing a critical building block for the development of active pharmaceutical ingredients (APIs), particularly in enantioselective synthesis. This compound is essential for research and production facilities in the pharmaceutical and fine chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug research.
• Asymmetric Synthesis: Used in the preparation of enantiomerically pure compounds, leveraging the chiral center for stereoselective reactions.
• Peptidomimetics Research: Serves as a precursor for non-peptide structures that mimic peptides, important in drug discovery for metabolic diseases.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organocatalysts for use in homogeneous catalysis.
• Academic & R&D Laboratories: Used in medicinal chemistry and organic synthesis research for method development and compound library generation.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and agrochemical intermediates.

Basic Information

Product Name	4-(1-Amino-Ethyl)-Benzoic Acid Methyl Ester Hydrochloride
CAS No.	934388-45-1
Molecular Formula	C10H14ClNO2
Molecular Weight	215.68 g/mol
Synonyms	Methyl 4-(1-Aminoethyl)benzoate hydrochloride; Benzoic acid, 4-(1-aminoethyl)-, methyl ester, hydrochloride; Methyl 4-(α-aminoethyl)benzoate HCl; (R/S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride; 4-(Aminoethyl)benzoic acid methyl ester hydrochloride; p-(1-Aminoethyl)benzoic acid methyl ester HCl; Methyl p-(α-aminoethyl)benzoate hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(1-Amino-Ethyl)-Benzoic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.